A Tactical Approach to Writing Your Grant Application (HSR) - 2023

Nov 6, 20230 likes10 views

CTSI R Workshop: A Tactical Approach to Writing Your Grant Application (HSR) Tannaz Moin, MD, MBA, MSHS Associate Professor of Medicine at UCLA Associate Director, UCLA Specialty Training and Advanced Research (STAR) Program

A Tactical Approach
to Writing Your
Grant Proposal
Tannaz Moin, MD, MBA, MSHS
UCLA CTSI R Workshop
November 2, 2023
Special thanks to Drs. Catherine Sarkisian and O. Kenrik Duru

4-6 Month Time-line:
1st month
• Pick a high-impact topic you love and get excited to be creative
o Should be natural extension of your K work
• Draft Specific Aims
• Start to put together scientific team
• Meet with admin team – map out calendar and divide up tasks
o Find out who can help you and identify key dates
(i.e., resources, budget, DSMP, figures, references etc. . . )
o Set target dates to get drafts to Co-Is
• Consider vacations, hospital attending etc.
• Schedule CTSI grant studio if possible

3-4 Months Out:
Meet with your
Program Official
• Remember that most PO’s love seeing K
awardees get R01s
o Relationship evolves during your K
• Will he/she/they will read your specific aims?
• Suggestions re study section?
• (Cover letter can mention your PO)
• (Send thank you email and copy of grant)

Putting Together Your Team:
Think Both as a Reviewer and as PI
• Interdisciplinary teams are increasingly important
• Each team member needs to be making unique/
complimentary contribution (avoid overlap)
• Consider linking with strengths of your institution
• Will be attractive to reviewers
• Good opportunity to expand your network

Putting Your Team
Together (Continued)
• Think carefully about subcontracts
(allow extra time)
• Balance of seniority levels
• Think about division needs
• Choose people you want to work with

Developing
your Team
Leadership
Style
• Embrace the role of PI (gradual process
evolving over K period)
• Emulate PI’s you admire
• Consider formal leadership training
• Be very clear to Co-I’s what is expected
• Exact role?
• How many meetings? Format? Travel?
• What % time covered?
• Authorship?

Start Budget Early
• Tension between being economical and practical (talk to your PO)
• Agencies like low-budget projects BUT
• Make sure you can do the work!
• And, likely to get across the board cuts
• Budget justification is CRITICAL
• Investigator time:
• As new investigator consider 35% time
• 5% time for Co-Is can be red flag to reviewers

Don’t Under-budget:
• Project Director salary
• Ground transportation for staff
• Cell phones and service
• Translations
• Data storage
• Publication fees for open access journals

Writing
Your
Grant
• Approach (Methods) is MOST important
• Write first. Do not wait.
• Remember your audience
• Few MDs
• May know nothing about your area of research
• Make it easy on the reviewer
• White space, figures, tables, colors

Telling Your Story:
Preliminary Studies
• Purpose:
• (Findings that support your
hypotheses)
• Most important: to show the
reviewer your team has
experience to do the project

• Discuss trade-offs of your
design decisions
• Example: randomizing at
individual vs. cluster?
• Can do this throughout or in
summary section towards end
of approach section
• How will you deal with
potential problems?
Show that you have
considered potential
obstacles/ tradeoffs
and how you will
address them

Make it Easy for the Reviewer
• Use exact language from program
announcement
o “the stated aim of this program announcement is
XXX and our project addresses this by . . . . “
• Remind reviewer of specific review criteria
and state specifically how your project
addresses
o Consider bulleted sections
o Significance
o Investigators
o Innovation
o Approach
o Environment

Avoid Common Pitfalls
• Write face page (abstract) early and circulate
• Don’t be unjustifiably overambitious
• Convince reviewer of feasibility
• Preliminary studies
• Benchmarks
• Alternative plans
• Institutional support
• HAVE FUN!

This document provides guidance on developing a strategic plan for research and writing successful grant proposals. It outlines developing a strategic plan that includes research themes, available and needed resources, and dissemination plans. It also discusses writing proposals, including staking your claim, professional synergies, contacting program officers, establishing credibility, structure, style, citations, and responding to reviews. Key points include developing long-term research goals, tailoring proposals to specific programs, addressing both intellectual merit and broader impacts, and revising proposals in response to reviewer feedback.

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A Tactical Approach to Writing Your Grant Application (HSR) - 2023

1. A Tactical Approach to Writing Your Grant Proposal Tannaz Moin, MD, MBA, MSHS UCLA CTSI R Workshop November 2, 2023 Special thanks to Drs. Catherine Sarkisian and O. Kenrik Duru

2. 4-6 Month Time-line: 1st month • Pick a high-impact topic you love and get excited to be creative o Should be natural extension of your K work • Draft Specific Aims • Start to put together scientific team • Meet with admin team – map out calendar and divide up tasks o Find out who can help you and identify key dates (i.e., resources, budget, DSMP, figures, references etc. . . ) o Set target dates to get drafts to Co-Is • Consider vacations, hospital attending etc. • Schedule CTSI grant studio if possible

3. 3-4 Months Out: Meet with your Program Official • Remember that most PO’s love seeing K awardees get R01s o Relationship evolves during your K • Will he/she/they will read your specific aims? • Suggestions re study section? • (Cover letter can mention your PO) • (Send thank you email and copy of grant)

4. Putting Together Your Team: Think Both as a Reviewer and as PI • Interdisciplinary teams are increasingly important • Each team member needs to be making unique/ complimentary contribution (avoid overlap) • Consider linking with strengths of your institution • Will be attractive to reviewers • Good opportunity to expand your network

5. Putting Your Team Together (Continued) • Think carefully about subcontracts (allow extra time) • Balance of seniority levels • Think about division needs • Choose people you want to work with

6. Developing your Team Leadership Style • Embrace the role of PI (gradual process evolving over K period) • Emulate PI’s you admire • Consider formal leadership training • Be very clear to Co-I’s what is expected • Exact role? • How many meetings? Format? Travel? • What % time covered? • Authorship?

7. Start Budget Early • Tension between being economical and practical (talk to your PO) • Agencies like low-budget projects BUT • Make sure you can do the work! • And, likely to get across the board cuts • Budget justification is CRITICAL • Investigator time: • As new investigator consider 35% time • 5% time for Co-Is can be red flag to reviewers

8. Don’t Under-budget: • Project Director salary • Ground transportation for staff • Cell phones and service • Translations • Data storage • Publication fees for open access journals

9. Writing Your Grant • Approach (Methods) is MOST important • Write first. Do not wait. • Remember your audience • Few MDs • May know nothing about your area of research • Make it easy on the reviewer • White space, figures, tables, colors

10. Telling Your Story: Preliminary Studies • Purpose: • (Findings that support your hypotheses) • Most important: to show the reviewer your team has experience to do the project

11. • Discuss trade-offs of your design decisions • Example: randomizing at individual vs. cluster? • Can do this throughout or in summary section towards end of approach section • How will you deal with potential problems? Show that you have considered potential obstacles/ tradeoffs and how you will address them

12. Make it Easy for the Reviewer • Use exact language from program announcement o “the stated aim of this program announcement is XXX and our project addresses this by . . . . “ • Remind reviewer of specific review criteria and state specifically how your project addresses o Consider bulleted sections o Significance o Investigators o Innovation o Approach o Environment

13. Avoid Common Pitfalls • Write face page (abstract) early and circulate • Don’t be unjustifiably overambitious • Convince reviewer of feasibility • Preliminary studies • Benchmarks • Alternative plans • Institutional support • HAVE FUN!

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