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A Tactical Approach
to Writing Your
Grant Proposal
Tannaz Moin, MD, MBA, MSHS
UCLA CTSI R Workshop
December 8, 2022
Special thanks to Drs. Catherine Sarkisian and O. Kenrik Duru
4-6 Month Time-line:
1st month
 Pick a high-impact topic you love and get excited to be creative
o Should be natural extension of your K work
 Draft Specific Aims
 Start to put together scientific team
 Meet with admin team  map out calendar and divide up tasks
o Find out who can help you and what key dates are
(i.e., resources, budget, DSMP, figures, references etc. . . )
o Set target dates to get drafts to Co-Is
 Consider vacations, hospital attending etc.
 Schedule CTSI grant studio if possible
3-4 Months Out:
Meet with your
Program Official
 Remember that most POs love seeing K
awardees get R01s
o Relationship evolves during your K
 Phone vs. email?
 Will he/she/they will read your specific aims?
 Suggestions re study section?
 (Cover letter can mention your PO)
 (Send thank you email and copy of grant)
Putting Together Your Team:
Think Both as a Reviewer and as PI
 Interdisciplinary teams are increasingly important
 Each team member needs to be making unique/
complimentary contribution (avoid overlap)
 Consider linking with strengths of your institution
 Will be attractive to reviewers
 Good opportunity to expand your network
Putting Your Team
Together (Continued)
 Think carefully about subcontracts
(allow extra time)
 Balance of seniority levels
 Think about division needs
 Choose people you want to work with
Developing
your Team
Leadership
Style
 Embrace the role of PI (gradual process
evolving over K period)
 Emulate PIs you admire
 Consider formal leadership training
 Be very clear to Co-Is what is expected
 Exact role?
 How many meetings? Format? Travel?
 What % time covered?
 Authorship?
Start Budget Early
 Tension between being economical and practical (talk to your PO)
 Agencies like low-budget projects BUT
 Make sure you can do the work!
 And, likely to get across the board cuts
 Budget justification is CRITICAL
 Investigator time:
 As new investigator consider 35% time
 5% time for Co-Is can be red flag to reviewers
Dont Under-budget:
 Project Director salary
 Ground transportation for staff
 Cell phones and service
 Translations
 Data storage
 Publication fees for open access journals
Writing
Your
Grant
 Approach (Methods) is MOST important
 Write first. Do not wait.
 Remember your audience
 Few MDs
 May know nothing about your area of research
 Make it easy on the reviewer
 White space, figures, tables, colors
Telling Your Story:
Preliminary Studies
 Purpose:
 (Findings that support your
hypotheses)
 Most important: to show the
reviewer your team has
experience to do the project
 Discuss trade-offs of your
design decisions
 Example: randomizing at
individual vs. cluster?
 Can do this throughout or in
summary section towards end
of approach section
 How will you deal with
potential problems?
Show that you have
considered potential
obstacles/ tradeoffs
and how you will
address them
Make it Easy for the Reviewer
 Use exact language from program
announcement
o the stated aim of this program announcement is
XXX and our project addresses this by . . . . 
 Remind reviewer of specific review criteria
and state specifically how your project
addresses
o Consider bulleted sections
o Significance
o Investigators
o Innovation
o Approach
o Environment
Avoid Common Pitfalls
 Write face page (abstract) early and circulate
 Dont be unjustifiably overambitious
 Convince reviewer of feasibility
 Preliminary studies
 Benchmarks
 Alternative plans
 Institutional support
 HAVE FUN!

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A Tactical Approach to Writing Your Grant Application. (Moin, 2022)

  • 1. A Tactical Approach to Writing Your Grant Proposal Tannaz Moin, MD, MBA, MSHS UCLA CTSI R Workshop December 8, 2022 Special thanks to Drs. Catherine Sarkisian and O. Kenrik Duru
  • 2. 4-6 Month Time-line: 1st month Pick a high-impact topic you love and get excited to be creative o Should be natural extension of your K work Draft Specific Aims Start to put together scientific team Meet with admin team map out calendar and divide up tasks o Find out who can help you and what key dates are (i.e., resources, budget, DSMP, figures, references etc. . . ) o Set target dates to get drafts to Co-Is Consider vacations, hospital attending etc. Schedule CTSI grant studio if possible
  • 3. 3-4 Months Out: Meet with your Program Official Remember that most POs love seeing K awardees get R01s o Relationship evolves during your K Phone vs. email? Will he/she/they will read your specific aims? Suggestions re study section? (Cover letter can mention your PO) (Send thank you email and copy of grant)
  • 4. Putting Together Your Team: Think Both as a Reviewer and as PI Interdisciplinary teams are increasingly important Each team member needs to be making unique/ complimentary contribution (avoid overlap) Consider linking with strengths of your institution Will be attractive to reviewers Good opportunity to expand your network
  • 5. Putting Your Team Together (Continued) Think carefully about subcontracts (allow extra time) Balance of seniority levels Think about division needs Choose people you want to work with
  • 6. Developing your Team Leadership Style Embrace the role of PI (gradual process evolving over K period) Emulate PIs you admire Consider formal leadership training Be very clear to Co-Is what is expected Exact role? How many meetings? Format? Travel? What % time covered? Authorship?
  • 7. Start Budget Early Tension between being economical and practical (talk to your PO) Agencies like low-budget projects BUT Make sure you can do the work! And, likely to get across the board cuts Budget justification is CRITICAL Investigator time: As new investigator consider 35% time 5% time for Co-Is can be red flag to reviewers
  • 8. Dont Under-budget: Project Director salary Ground transportation for staff Cell phones and service Translations Data storage Publication fees for open access journals
  • 9. Writing Your Grant Approach (Methods) is MOST important Write first. Do not wait. Remember your audience Few MDs May know nothing about your area of research Make it easy on the reviewer White space, figures, tables, colors
  • 10. Telling Your Story: Preliminary Studies Purpose: (Findings that support your hypotheses) Most important: to show the reviewer your team has experience to do the project
  • 11. Discuss trade-offs of your design decisions Example: randomizing at individual vs. cluster? Can do this throughout or in summary section towards end of approach section How will you deal with potential problems? Show that you have considered potential obstacles/ tradeoffs and how you will address them
  • 12. Make it Easy for the Reviewer Use exact language from program announcement o the stated aim of this program announcement is XXX and our project addresses this by . . . . Remind reviewer of specific review criteria and state specifically how your project addresses o Consider bulleted sections o Significance o Investigators o Innovation o Approach o Environment
  • 13. Avoid Common Pitfalls Write face page (abstract) early and circulate Dont be unjustifiably overambitious Convince reviewer of feasibility Preliminary studies Benchmarks Alternative plans Institutional support HAVE FUN!