Lithium toxicity HY
•
0 likes•13 views
Lithium toxicity can occur from acute overdose or chronic use. Acute toxicity presents with gastrointestinal issues like nausea and vomiting, while chronic toxicity presents with neurological symptoms like lethargy, confusion, and ataxia. Treatment involves intravenous hydration and hemodialysis in severe cases to remove lithium from the body and decrease toxicity.
Lithium toxicity HY
- 1. Lithium toxicity Etiology Acute toxicity • Intentional overdose Chronic toxicity • Decreased renal perfusion (↓ lithium clearance) • Dehydration • Thiazide diuretics, NSAIDs, ACE inhibitors Clinical features Acute toxicity • Gastrointestinal: nausea, vomiting, diarrhea • Late neurologic sequelae Chronic toxicity (neurologic) • Lethargy, confusion, agitation • Ataxia, tremor/fasciculations, seizure Treatment • Intravenous hydration • Hemodialysis (severe cases)