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L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03




 S       D NG STATA 10.0 PHN TCH TH NG K
            TRONG NGHIN C U KHOA H C

                        KI M            NH GI THI T
                                                             TS. BS T ng Kim H ng

1. Ki m nh s trung b狸nh
       1.1 Ki m nh 1 s trung b狸nh




  M file PULSE ph但n t鱈ch.
- L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> One
sample mean comparison test -> Ch n bi n s c n ki m nh v gi叩 tr c n ki m nh, v鱈
d ch n bi n s Pulse1v hypothezied value la 80 -> Submit
(Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達                c th a)




                                                                                  1
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03




    t qu c坦      c nh sau:
. ttest pulse1 == 80
One-sample t test
------------------------------------------------------------------------------
Variable |     Obs        Mean    Std. Err.   Std. Dev.   [95% Conf. Interval]
---------+--------------------------------------------------------------------
  pulse1 |      92    72.86957    1.147737    11.00871    70.58973     75.1494
------------------------------------------------------------------------------
    mean = mean(pulse1)                                            t = -6.2126
Ho: mean = 80                                    degrees of freedom =       91
    Ha: mean < 80                   Ha: mean != 80                  Ha: mean > 80
 Pr(T < t) = 0.0000             Pr(|T| > |t|) = 0.0000           Pr(T > t) = 1.0000

T k t qu ny, ta th y r ng: V狸 gi叩 tr p <0.0001, n棚n ch炭ng ta lo i b H0 v k t lu n
r ng d a tr棚n m u ny, trung b狸nh m ch c a b nh nh但n trong d但n s kh叩c bi t v i gi叩 tr
80 l n/ph炭t m t c叩ch c坦 箪 ngh a
- T鱈nh v i s c坦 s n, l nh s d ng trong STATA nh sau:
ttesti n x s 袖 0
V鱈 d v i m u 50 b nh nh但n, c坦 trung b狸nh amylase huy t thanh l 96 v/ml,            l ch
chu n 35, ta c坦 th ch!ng minh trung b狸nh amylase huy t thanh trong d但n s c坦 th c s
kh叩c v i gi叩 tr 120 v/ml kh担ng?
- L nh trong SATAT:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> One
sample mean comparison calculator




                                                                                      2
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03




    t qu c坦      c nh sau:
. ttesti 50 96 35 120
One-sample t test
------------------------------------------------------------------------------
         |     Obs        Mean    Std. Err.   Std. Dev.   [95% Conf. Interval]
---------+--------------------------------------------------------------------
       x |      50          96    4.949747          35    86.05311     105.9469
------------------------------------------------------------------------------
    mean = mean(x)                                                 t = -4.8487
Ho: mean = 120                                   degrees of freedom =        49
   Ha: mean < 120                   Ha: mean != 120             Ha: mean > 120
 Pr(T < t) = 0.0000             Pr(|T| > |t|) = 0.0000        Pr(T > t) = 1.0000

T k t qu ny, ta th y r ng: V狸 gi叩 tr p <0.0001, n棚n ch炭ng ta lo i b H0 v k t lu n
r ng d a tr棚n m u ny, trung b狸nh amylase huy t thanh c a d但n s kh叩c bi t v i gi叩 tr
120 v/ml m t c叩ch c坦 箪 ngh a
         1.2 Ki m nh s kh叩c bi t c a 2 s trung b狸nh
                1.2.1 Ki m nh s kh叩c bi t c a 2 s trung b狸nh l y t 2 m u kh叩c
nhau
- L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two
sample mean comparison test -> Ch n 2 bi n s c n so s叩nh s trung b狸nh -> Submit
- T鱈nh v i s c坦 s n, l nh s d ng trong STATA nh sau:
ttesti n1 x1 s1 n2 x2 s2
V鱈 d : M t nh坦m nghi棚n c!u thu th p s li u amylase huy t thanh t m t m u g m
nh"ng ng i kh e m nh v 1 m u t nh"ng b nh nh但n trong b nh vi n. Nh坦m NC mu n
bi t trung b狸nh amylase huy t thanh c a 2 d但n s c坦 kh叩c nhau hay kh担ng. D" li u v 2
m u nh sau:
M u                     n    x       SD
Ng i kh e m nh          50   96      35
B nh nh但n               60   120 40


                                                                                   3
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03


- L nh trong STATA:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two
sample mean comparison calculator




    t qu c坦      c nh sau:
. ttesti 50 96 35 60 120 40
Two-sample t test with equal variances
------------------------------------------------------------------------------
         |     Obs        Mean    Std. Err.   Std. Dev.   [95% Conf. Interval]
---------+--------------------------------------------------------------------
       x |      50           96   4.949747          35    86.05311     105.9469
       y |      60         120    5.163978          40    109.6669     130.3331
---------+--------------------------------------------------------------------
combined |     110    109.0909    3.766917    39.50776     101.625     116.5568
---------+--------------------------------------------------------------------
    diff |                 -24    7.240735               -38.35239    -9.647607
------------------------------------------------------------------------------
    diff = mean(x) - mean(y)                                       t = -3.3146
Ho: diff = 0                                     degrees of freedom =       108
    Ha: diff < 0                     Ha: diff != 0                    Ha: diff > 0
 Pr(T < t) = 0.0006             Pr(|T| > |t|) = 0.0013             Pr(T > t) = 0.9994

T k t qu ny, ta th y r ng: V狸 gi叩 tr p = 0.0013 <0.05, n棚n ch炭ng ta lo i b H0 v k t
lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c 箪 ngh a 5% r ng trung b狸nh
amylase huy t thanh c a d但n s ng i b狸nh th ng v ng i b nh kh叩c bi t nhau m t
c叩ch c坦 箪 ngh a.
* L u 箪: Tr c khi so s叩nh 2 s trung b狸nh c n ph i ki m nh xem ph ng sai c坦 b ng
nhau hay kh担ng      quy t nh ch#n ph ng sai b ng nhau hay kh担ng b ng nhau khi lm
ph辿p ki m t (s$ gi i th鱈ch r探 trong ph n d i 但y)
* Ki m nh s kh叩c bi t c a 2 s trung b狸nh l y t 2 nh坦m
  M file PULSE ph但n t鱈ch.
- V鱈 d : ch炭ng ta c n so s叩nh trung b狸nh c但n n%ng c a 2 nh坦m nam v n"
- Tr c ti棚n ch炭ng ta c n so s叩nh ph ng sai c a hai nh坦m        xem ph ng sai c坦 b ng
nhau hay kh担ng.


                                                                                        4
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03


L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two group
variance comparison test -> Ch n bi n s c n ki m nh (weigh) v bi n s ph但n nh坦m
(sex) -> Submit
(Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達                c th a)




    t qu c坦      c nh sau:
. sdtest weight, by(sex)
Variance ratio test
------------------------------------------------------------------------------
   Group |     Obs        Mean    Std. Err.   Std. Dev.   [95% Conf. Interval]
---------+--------------------------------------------------------------------
       1 |      57    69.82456    1.100274    8.306888    67.62045     72.02868
       2 |      35    54.57143    .9977165     5.90257    52.54382     56.59903
---------+--------------------------------------------------------------------
combined |      92    64.02174    1.098035    10.53198    61.84063     66.20285
------------------------------------------------------------------------------
    ratio = sd(1) / sd(2)                                          f =   1.9806
Ho: ratio = 1                                    degrees of freedom =    56, 34
    Ha: ratio < 1                   Ha: ratio != 1                   Ha: ratio > 1
  Pr(F < f) = 0.9825             2*Pr(F > f) = 0.0351             Pr(F > f) = 0.0175

H0: T& s 2 ph ng sai (sd1 v sd2) b ng 1, t!c l sd1 = sd2
T k t qu ny, ta th y r ng: V狸 gi叩 tr p = 0.0351 <0.05, n棚n ch炭ng ta lo i b H0 (2
ph ng sai b ng nhau) v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n
m!c 箪 ngh a 5% r ng ph ng sai c a c但n n%ng nam v n" kh叩c bi t nhau m t c叩ch c坦
箪 ngh a.
- Sau khi 達 x叩c nh l ph ng sai c a 2 m u kh担ng b ng nhau, ta so s叩nh 2 s trung
b狸nh c a 2 m u (v i i u ki n ph ng sai kh担ng b ng nhau)
L nh s d ng trong STATA nh sau:




                                                                                        5
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03


+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two group
mean comparison test -> Ch n bi n s c n ki m nh (weigh) v bi n s ph但n nh坦m (sex)
-> Ch n unequal variances -> Submit
(Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達                c th a)
    t qu c坦      c nh sau:
. ttest weight, by(sex) unequal
Two-sample t test with unequal variances
------------------------------------------------------------------------------
   Group |     Obs        Mean    Std. Err.   Std. Dev.   [95% Conf. Interval]
---------+--------------------------------------------------------------------
       1 |      57    69.82456    1.100274    8.306888    67.62045     72.02868
       2 |      35    54.57143    .9977165     5.90257    52.54382     56.59903
---------+--------------------------------------------------------------------
combined |      92    64.02174    1.098035    10.53198    61.84063     66.20285
---------+--------------------------------------------------------------------
    diff |            15.25313    1.485275                12.30145     18.20481
------------------------------------------------------------------------------
    diff = mean(1) - mean(2)                                       t = 10.2696
Ho: diff = 0                     Satterthwaite's degrees of freedom = 87.9805
    Ha: diff < 0                     Ha: diff != 0                   Ha: diff > 0
 Pr(T < t) = 1.0000             Pr(|T| > |t|) = 0.0000            Pr(T > t) = 0.0000

H0: S kh叩c bi t 2 s trung b狸nh (mean1 v mean2) b ng 0, t!c l mean1 = mean2
T k t qu ny, ta th y r ng: V狸 gi叩 tr p < 0.0001, n棚n ch炭ng ta lo i b H0 (2 trung b狸nh
b ng nhau) v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c 箪 ngh a
5% r ng trung b狸nh c但n n%ng c a nam v n" kh叩c bi t nhau m t c叩ch c坦 箪 ngh a.
                1.2.2 Ki m nh s kh叩c bi t c a 2 s trung b狸nh l y t c湛ng 1 m u (so
s叩nh tr c-sau, so s叩nh c p
  M file PULSE ph但n t鱈ch.
- V鱈 d : ch炭ng ta c n so s叩nh trung b狸nh m ch tr c v sau khi d湛ng thu c c坦 kh叩c nhau
kh担ng
L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Mean
comparison test, paired data -> Ch n bi n s c n ki m nh -> Submit
(Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達                c th a)




                                                                                        6
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03




    t qu c坦      c nh sau:
. ttest pulse1 == pulse2
Paired t test
------------------------------------------------------------------------------
Variable |     Obs        Mean    Std. Err.   Std. Dev.   [95% Conf. Interval]
---------+--------------------------------------------------------------------
  pulse1 |      90    72.53333    1.141237    10.82673    70.26572     74.80095
  pulse2 |      90        78.8    1.601981    15.19772     75.6169      81.9831
---------+--------------------------------------------------------------------
    diff |      90   -6.266667    1.294259    12.27842   -8.838332    -3.695002
------------------------------------------------------------------------------
     mean(diff) = mean(pulse1 - pulse2)                            t = -4.8419
 Ho: mean(diff) = 0                              degrees of freedom =        89
 Ha: mean(diff) < 0               Ha: mean(diff) != 0          Ha: mean(diff) > 0
 Pr(T < t) = 0.0000             Pr(|T| > |t|) = 0.0000         Pr(T > t) = 1.0000

H0: Trung b狸nh c a s kh叩c bi t (pulse1 - pulse2) b ng 0
T k t qu ny, ta th y r ng: V狸 gi叩 tr p < 0.0001, n棚n ch炭ng ta lo i b H0 (trung b狸nh
c a s kh叩c bi t =0) v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c
箪 ngh a 5% r ng trung b狸nh c a s kh叩c bi t nh p m ch c a b nh nh但n tr c v sau khi
  i u tr kh叩c 0, hay n坦i c叩ch kh叩c trung b狸nh m ch c a b nh nh但n tr c v sau khi i u
tr kh叩c nhau m t c叩ch c坦 箪 ngh a.
2. Ki m nh t l
         2.1 Ki m nh 1 t l
- L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> One
sample proportion test -> Ch n bi n s c n ki m nh v gi叩 tr c n ki m nh, v鱈 d
ch n bi n s smoke v hypothezied value l 0.15 -> Submit




                                                                                    7
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03




        2.2 Ki m nh 2 t l
- L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two
sample proportion test -> Ch n bi n s c n ki m nh -> Submit
* Ki m nh s kh叩c bi t c a 2 t l l y t 2 nh坦m
  M file PULSE ph但n t鱈ch.
- V鱈 d : ch炭ng ta c n so s叩nh t& l h炭t thu c l叩 c a nam v n"
- L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two group
proportion test -> Ch n bi n s c n ki m nh (smokes) v bi n s ph但n nh坦m (sex) ->
Submit




                                                                                        8
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03




3. Ph辿p ki m chi-b狸nh ph ng (chi-square)
 M file PULSE ph但n t鱈ch.




                                                   9
L p Ph   ng ph叩p NCKH  Ch   ng tr狸nh CUD UPNT03


- L nh s d ng trong STATA nh sau:
+ Statistics -> Summaries, tables and tests -> Tables -> Two way tables with measures
of association -> Nh p bi n s cho hng v c t -> Ch n ph辿p ki m c n s d ng (v鱈 d
Chi-square hay Fishers exact test -> Submit
(N u mu n c坦 t l theo hng th狸 ch n th棚m within- row relative frequency, n u mu n
c坦 t l theo c t th狸 ch n th棚m within- column relative frequency)




- T鱈nh v i s c坦 s n, l nh s d ng trong STATA nh sau:
tabi a bc de f, chi 2
hay
tabi a bc de f, exact




                                                                                    10

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Su dung stata 3

  • 1. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 S D NG STATA 10.0 PHN TCH TH NG K TRONG NGHIN C U KHOA H C KI M NH GI THI T TS. BS T ng Kim H ng 1. Ki m nh s trung b狸nh 1.1 Ki m nh 1 s trung b狸nh M file PULSE ph但n t鱈ch. - L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> One sample mean comparison test -> Ch n bi n s c n ki m nh v gi叩 tr c n ki m nh, v鱈 d ch n bi n s Pulse1v hypothezied value la 80 -> Submit (Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達 c th a) 1
  • 2. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 t qu c坦 c nh sau: . ttest pulse1 == 80 One-sample t test ------------------------------------------------------------------------------ Variable | Obs Mean Std. Err. Std. Dev. [95% Conf. Interval] ---------+-------------------------------------------------------------------- pulse1 | 92 72.86957 1.147737 11.00871 70.58973 75.1494 ------------------------------------------------------------------------------ mean = mean(pulse1) t = -6.2126 Ho: mean = 80 degrees of freedom = 91 Ha: mean < 80 Ha: mean != 80 Ha: mean > 80 Pr(T < t) = 0.0000 Pr(|T| > |t|) = 0.0000 Pr(T > t) = 1.0000 T k t qu ny, ta th y r ng: V狸 gi叩 tr p <0.0001, n棚n ch炭ng ta lo i b H0 v k t lu n r ng d a tr棚n m u ny, trung b狸nh m ch c a b nh nh但n trong d但n s kh叩c bi t v i gi叩 tr 80 l n/ph炭t m t c叩ch c坦 箪 ngh a - T鱈nh v i s c坦 s n, l nh s d ng trong STATA nh sau: ttesti n x s 袖 0 V鱈 d v i m u 50 b nh nh但n, c坦 trung b狸nh amylase huy t thanh l 96 v/ml, l ch chu n 35, ta c坦 th ch!ng minh trung b狸nh amylase huy t thanh trong d但n s c坦 th c s kh叩c v i gi叩 tr 120 v/ml kh担ng? - L nh trong SATAT: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> One sample mean comparison calculator 2
  • 3. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 t qu c坦 c nh sau: . ttesti 50 96 35 120 One-sample t test ------------------------------------------------------------------------------ | Obs Mean Std. Err. Std. Dev. [95% Conf. Interval] ---------+-------------------------------------------------------------------- x | 50 96 4.949747 35 86.05311 105.9469 ------------------------------------------------------------------------------ mean = mean(x) t = -4.8487 Ho: mean = 120 degrees of freedom = 49 Ha: mean < 120 Ha: mean != 120 Ha: mean > 120 Pr(T < t) = 0.0000 Pr(|T| > |t|) = 0.0000 Pr(T > t) = 1.0000 T k t qu ny, ta th y r ng: V狸 gi叩 tr p <0.0001, n棚n ch炭ng ta lo i b H0 v k t lu n r ng d a tr棚n m u ny, trung b狸nh amylase huy t thanh c a d但n s kh叩c bi t v i gi叩 tr 120 v/ml m t c叩ch c坦 箪 ngh a 1.2 Ki m nh s kh叩c bi t c a 2 s trung b狸nh 1.2.1 Ki m nh s kh叩c bi t c a 2 s trung b狸nh l y t 2 m u kh叩c nhau - L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two sample mean comparison test -> Ch n 2 bi n s c n so s叩nh s trung b狸nh -> Submit - T鱈nh v i s c坦 s n, l nh s d ng trong STATA nh sau: ttesti n1 x1 s1 n2 x2 s2 V鱈 d : M t nh坦m nghi棚n c!u thu th p s li u amylase huy t thanh t m t m u g m nh"ng ng i kh e m nh v 1 m u t nh"ng b nh nh但n trong b nh vi n. Nh坦m NC mu n bi t trung b狸nh amylase huy t thanh c a 2 d但n s c坦 kh叩c nhau hay kh担ng. D" li u v 2 m u nh sau: M u n x SD Ng i kh e m nh 50 96 35 B nh nh但n 60 120 40 3
  • 4. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 - L nh trong STATA: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two sample mean comparison calculator t qu c坦 c nh sau: . ttesti 50 96 35 60 120 40 Two-sample t test with equal variances ------------------------------------------------------------------------------ | Obs Mean Std. Err. Std. Dev. [95% Conf. Interval] ---------+-------------------------------------------------------------------- x | 50 96 4.949747 35 86.05311 105.9469 y | 60 120 5.163978 40 109.6669 130.3331 ---------+-------------------------------------------------------------------- combined | 110 109.0909 3.766917 39.50776 101.625 116.5568 ---------+-------------------------------------------------------------------- diff | -24 7.240735 -38.35239 -9.647607 ------------------------------------------------------------------------------ diff = mean(x) - mean(y) t = -3.3146 Ho: diff = 0 degrees of freedom = 108 Ha: diff < 0 Ha: diff != 0 Ha: diff > 0 Pr(T < t) = 0.0006 Pr(|T| > |t|) = 0.0013 Pr(T > t) = 0.9994 T k t qu ny, ta th y r ng: V狸 gi叩 tr p = 0.0013 <0.05, n棚n ch炭ng ta lo i b H0 v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c 箪 ngh a 5% r ng trung b狸nh amylase huy t thanh c a d但n s ng i b狸nh th ng v ng i b nh kh叩c bi t nhau m t c叩ch c坦 箪 ngh a. * L u 箪: Tr c khi so s叩nh 2 s trung b狸nh c n ph i ki m nh xem ph ng sai c坦 b ng nhau hay kh担ng quy t nh ch#n ph ng sai b ng nhau hay kh担ng b ng nhau khi lm ph辿p ki m t (s$ gi i th鱈ch r探 trong ph n d i 但y) * Ki m nh s kh叩c bi t c a 2 s trung b狸nh l y t 2 nh坦m M file PULSE ph但n t鱈ch. - V鱈 d : ch炭ng ta c n so s叩nh trung b狸nh c但n n%ng c a 2 nh坦m nam v n" - Tr c ti棚n ch炭ng ta c n so s叩nh ph ng sai c a hai nh坦m xem ph ng sai c坦 b ng nhau hay kh担ng. 4
  • 5. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two group variance comparison test -> Ch n bi n s c n ki m nh (weigh) v bi n s ph但n nh坦m (sex) -> Submit (Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達 c th a) t qu c坦 c nh sau: . sdtest weight, by(sex) Variance ratio test ------------------------------------------------------------------------------ Group | Obs Mean Std. Err. Std. Dev. [95% Conf. Interval] ---------+-------------------------------------------------------------------- 1 | 57 69.82456 1.100274 8.306888 67.62045 72.02868 2 | 35 54.57143 .9977165 5.90257 52.54382 56.59903 ---------+-------------------------------------------------------------------- combined | 92 64.02174 1.098035 10.53198 61.84063 66.20285 ------------------------------------------------------------------------------ ratio = sd(1) / sd(2) f = 1.9806 Ho: ratio = 1 degrees of freedom = 56, 34 Ha: ratio < 1 Ha: ratio != 1 Ha: ratio > 1 Pr(F < f) = 0.9825 2*Pr(F > f) = 0.0351 Pr(F > f) = 0.0175 H0: T& s 2 ph ng sai (sd1 v sd2) b ng 1, t!c l sd1 = sd2 T k t qu ny, ta th y r ng: V狸 gi叩 tr p = 0.0351 <0.05, n棚n ch炭ng ta lo i b H0 (2 ph ng sai b ng nhau) v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c 箪 ngh a 5% r ng ph ng sai c a c但n n%ng nam v n" kh叩c bi t nhau m t c叩ch c坦 箪 ngh a. - Sau khi 達 x叩c nh l ph ng sai c a 2 m u kh担ng b ng nhau, ta so s叩nh 2 s trung b狸nh c a 2 m u (v i i u ki n ph ng sai kh担ng b ng nhau) L nh s d ng trong STATA nh sau: 5
  • 6. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two group mean comparison test -> Ch n bi n s c n ki m nh (weigh) v bi n s ph但n nh坦m (sex) -> Ch n unequal variances -> Submit (Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達 c th a) t qu c坦 c nh sau: . ttest weight, by(sex) unequal Two-sample t test with unequal variances ------------------------------------------------------------------------------ Group | Obs Mean Std. Err. Std. Dev. [95% Conf. Interval] ---------+-------------------------------------------------------------------- 1 | 57 69.82456 1.100274 8.306888 67.62045 72.02868 2 | 35 54.57143 .9977165 5.90257 52.54382 56.59903 ---------+-------------------------------------------------------------------- combined | 92 64.02174 1.098035 10.53198 61.84063 66.20285 ---------+-------------------------------------------------------------------- diff | 15.25313 1.485275 12.30145 18.20481 ------------------------------------------------------------------------------ diff = mean(1) - mean(2) t = 10.2696 Ho: diff = 0 Satterthwaite's degrees of freedom = 87.9805 Ha: diff < 0 Ha: diff != 0 Ha: diff > 0 Pr(T < t) = 1.0000 Pr(|T| > |t|) = 0.0000 Pr(T > t) = 0.0000 H0: S kh叩c bi t 2 s trung b狸nh (mean1 v mean2) b ng 0, t!c l mean1 = mean2 T k t qu ny, ta th y r ng: V狸 gi叩 tr p < 0.0001, n棚n ch炭ng ta lo i b H0 (2 trung b狸nh b ng nhau) v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c 箪 ngh a 5% r ng trung b狸nh c但n n%ng c a nam v n" kh叩c bi t nhau m t c叩ch c坦 箪 ngh a. 1.2.2 Ki m nh s kh叩c bi t c a 2 s trung b狸nh l y t c湛ng 1 m u (so s叩nh tr c-sau, so s叩nh c p M file PULSE ph但n t鱈ch. - V鱈 d : ch炭ng ta c n so s叩nh trung b狸nh m ch tr c v sau khi d湛ng thu c c坦 kh叩c nhau kh担ng L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Mean comparison test, paired data -> Ch n bi n s c n ki m nh -> Submit (Gi s gi nh v ph但n ph i b狸nh th ng c a bi n s 達 c th a) 6
  • 7. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 t qu c坦 c nh sau: . ttest pulse1 == pulse2 Paired t test ------------------------------------------------------------------------------ Variable | Obs Mean Std. Err. Std. Dev. [95% Conf. Interval] ---------+-------------------------------------------------------------------- pulse1 | 90 72.53333 1.141237 10.82673 70.26572 74.80095 pulse2 | 90 78.8 1.601981 15.19772 75.6169 81.9831 ---------+-------------------------------------------------------------------- diff | 90 -6.266667 1.294259 12.27842 -8.838332 -3.695002 ------------------------------------------------------------------------------ mean(diff) = mean(pulse1 - pulse2) t = -4.8419 Ho: mean(diff) = 0 degrees of freedom = 89 Ha: mean(diff) < 0 Ha: mean(diff) != 0 Ha: mean(diff) > 0 Pr(T < t) = 0.0000 Pr(|T| > |t|) = 0.0000 Pr(T > t) = 1.0000 H0: Trung b狸nh c a s kh叩c bi t (pulse1 - pulse2) b ng 0 T k t qu ny, ta th y r ng: V狸 gi叩 tr p < 0.0001, n棚n ch炭ng ta lo i b H0 (trung b狸nh c a s kh叩c bi t =0) v k t lu n r ng d a tr棚n s li u ny, ch炭ng ta c坦 th k t lu n m!c 箪 ngh a 5% r ng trung b狸nh c a s kh叩c bi t nh p m ch c a b nh nh但n tr c v sau khi i u tr kh叩c 0, hay n坦i c叩ch kh叩c trung b狸nh m ch c a b nh nh但n tr c v sau khi i u tr kh叩c nhau m t c叩ch c坦 箪 ngh a. 2. Ki m nh t l 2.1 Ki m nh 1 t l - L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> One sample proportion test -> Ch n bi n s c n ki m nh v gi叩 tr c n ki m nh, v鱈 d ch n bi n s smoke v hypothezied value l 0.15 -> Submit 7
  • 8. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 2.2 Ki m nh 2 t l - L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two sample proportion test -> Ch n bi n s c n ki m nh -> Submit * Ki m nh s kh叩c bi t c a 2 t l l y t 2 nh坦m M file PULSE ph但n t鱈ch. - V鱈 d : ch炭ng ta c n so s叩nh t& l h炭t thu c l叩 c a nam v n" - L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Classical tests of hypotheses -> Two group proportion test -> Ch n bi n s c n ki m nh (smokes) v bi n s ph但n nh坦m (sex) -> Submit 8
  • 9. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 3. Ph辿p ki m chi-b狸nh ph ng (chi-square) M file PULSE ph但n t鱈ch. 9
  • 10. L p Ph ng ph叩p NCKH Ch ng tr狸nh CUD UPNT03 - L nh s d ng trong STATA nh sau: + Statistics -> Summaries, tables and tests -> Tables -> Two way tables with measures of association -> Nh p bi n s cho hng v c t -> Ch n ph辿p ki m c n s d ng (v鱈 d Chi-square hay Fishers exact test -> Submit (N u mu n c坦 t l theo hng th狸 ch n th棚m within- row relative frequency, n u mu n c坦 t l theo c t th狸 ch n th棚m within- column relative frequency) - T鱈nh v i s c坦 s n, l nh s d ng trong STATA nh sau: tabi a bc de f, chi 2 hay tabi a bc de f, exact 10