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Pco en hirsutisme
1. PCO en HirsutismePCO en Hirsutisme
Dr. R. SchatsDr. R. Schats
IVF CentrumIVF Centrum
VU mcVU mc
2. PCO: de diagnosePCO: de diagnose
Oligomenorrhoe vanaf menarcheOligomenorrhoe vanaf menarche
Verhoogd serum LHVerhoogd serum LH
Polycysteuze ovaria (echoscopie)Polycysteuze ovaria (echoscopie)
AdipositasAdipositas
Hirsutisme (hyperandrogenisme)Hirsutisme (hyperandrogenisme)
InsulineresistentieInsulineresistentie
Infertiliteit door anovulatieInfertiliteit door anovulatie
3. PCO: de oorzakenPCO: de oorzaken
Onbekend !, 4% van alle vrouwenOnbekend !, 4% van alle vrouwen
ErfelijkErfelijk
Enzymdefici谷ntiesEnzymdefici谷nties
Te veel eicellenTe veel eicellen
4. PCO: de gevolgenPCO: de gevolgen
Vaak infertiliteitVaak infertiliteit
Adipositas, hirsutismeAdipositas, hirsutisme
Diabetes mellitus type IIDiabetes mellitus type II
Verhoogde kans opVerhoogde kans op
endometriumcarcinoomendometriumcarcinoom
Lange termijn: verhoogde kans opLange termijn: verhoogde kans op
hart en vaatziektenhart en vaatziekten
5. PCO: de behandelingPCO: de behandeling
Geen kinderwens:Geen kinderwens:
OAC (Diane)OAC (Diane)
Wel kinderwens:Wel kinderwens:
Ovulatie-inductieOvulatie-inductie
(aparte les)(aparte les)
9. PCO: SamenvattingPCO: Samenvatting
Meest voorkomende oorzaak vanMeest voorkomende oorzaak van
cyclusstoornissencyclusstoornissen
InfertiliteitInfertiliteit
Lange termijn effectenLange termijn effecten
10. HirsutismeHirsutisme
Beharingspatroon bij de vrouw inBeharingspatroon bij de vrouw in
mannelijke richtingmannelijke richting
Gestoorde interactie tussen androgenenGestoorde interactie tussen androgenen
en hun receptorenen hun receptoren
Balans spiegels en gevoeligheidBalans spiegels en gevoeligheid